In the radiological examination of the spine one frequently sees in association with kyphoses very varied contours of the upper and lower vertebral margins. Mechanical Compression and Nucleus Pulposus Application on Dorsal Root the disc core is presumed to contribute to intervertebral disc hernia-related pain. This report examines 18 surgically proven L3/4 herniated nucleus pulposus ( HNP), all having myelogram, CT and adequate neurological evaluation. It will focus.

Author: Kegami Yozshucage
Country: Saint Lucia
Language: English (Spanish)
Genre: Health and Food
Published (Last): 19 February 2012
Pages: 361
PDF File Size: 4.95 Mb
ePub File Size: 1.73 Mb
ISBN: 739-8-76743-512-8
Downloads: 39413
Price: Free* [*Free Regsitration Required]
Uploader: Gocage

It is located within the annulus fibrosus and between the vertebral body endplates. A Schematic drawing with a sciatic nerve and stimulation electrode; b dorsal root ganglion DRG for exposure to nucleus pulposus NP and light mechanical compression; c recording electrode at the surface of the spinal cord; d recording site in the ventral posterior lateral VPL nucleus.

Nucleus pulposus | Radiology Reference Article |

The popular term slipped disc is a misnomer, as the intervertebral discs are tightly sandwiched between two vertebrae to which they are attached, and cannot actually “slip”, or even get out of place.

Archived from the original on A critical review of risk and benefit”. The von Frey monofilaments were applied in order of increasing stiffness, starting with 0. Anesthesia was induced with isoflurane Baxter Medical AB.

Excess load is transferred to the anuluswhich may then develop fissures as a result.

Lateral L3/4 herniated nucleus pulposus: clinical and imaging considerations.

This disorder is called cauda equina syndrome. Disc herniations gernia result from general wear and tear, such as constant sitting or squatting, driving, or a sedentary lifestyle. Annals of Internal Medicine. Application of nucleus pulposus to L5 dorsal root ganglion in rats enhances nociceptive dorsal horn neuronal windup. Indian J Orthop ; Pathomechanisms of nerve root injury caused by disc herniation: Over-the-counter and hernia nukleus pulposus medications can often lessen inflammation, which allows patients to begin long-term treatments like physical therapy without excessive pain or discomfort.


Early effects of nucleus pulposus application on spinal nerve root morphology and function. Disc herniation can occur in any disc in the spine, but the two most common forms are lumbar disc herniation and cervical disc herniation.

Takahashi K, et al.

Thalamic activation in a disc herniation model. A positive withdrawal was scored when the animal responded to two out of three stimuli presented.

From Wikipedia, the free encyclopedia. Most authors favour degeneration of the intervertebral disc as the major cause of spinal disc pluposus and cite trauma as a low cause. The contribution of acute DRG compression and disc material leakage to changes in transmission in central neuronal networks is likely to be complex and to involve both short-term and long-term effects.

Probable candidate genes include type I collagen sp1 sitetype IX collagenvitamin D receptoraggrecanasporinEhrniainterleukin-1and interleukin-6 polymorphisms. The hydraulic effect hernia nukleus pulposus the contained, hydrated nucleus within the annulus acts as a shock absorber nukoeus cushion the spinal column from forces that are applied to the musculoskeletal system.

From Occiput to Coccyx”. Because there are various causes of back injuries, prevention must be comprehensive. Behavioral test One group of animals subjected nuklesu the same surgical procedures as in series 2 and 3 were tested for changes in paw withdrawal thresholds series 4; see Fig. This model has previously been shown to induce behavioral changes as determined by von Frey withdrawal tests 15 and video analysis of changes in spontaneous behavior 14 as well as morphological changes in the peripheral nervous system, such as changes in the herbia surrounding the DRG.

In contrast to a herniation, none of the central portion escapes beyond the outer layers. International Journal of Osteopathic Medicine.

Spinal disc herniation

Study design The aims of the present study were addressed in four different experimental series Fig. They can range from little or no pain, if the disc is the only tissue injured, to severe and unrelenting neck pain or low back pain that radiates into regions served by nerve roots which have been irritated or impinged by the herniated material.


For other uses, see Slipped disc disambiguation. Lumbar disc herniation occurs 15 times more than cervical disc herniation, and is an important cause of lower back pain [11] [14].

At this stage, no remnants of the previously applied NP were visible on macroscopic inspection. The review of Rasoul MR et al. Infobox medical condition new All articles with unsourced statements Nkleus with unsourced statements from December Articles with unsourced statements from March Commons category link is on Wikidata Articles with Curlie links Wikipedia articles with GND identifiers Wikipedia articles with NDL identifiers.

While sitting or bending to lift, internal pressure on a disc can move from 17 psi lying down to over psi lifting with a rounded back. The aim of the present study was to investigate possible changes in neuronal thalamic activity using an pukposus experimental disc hernia model in the rodent.

Hudkins PG, et al. This causes an oscillatory pressure to decrease pain. The disc is actually grown together with the adjacent vertebrae and can be squeezed, stretched and twisted, all in small degrees.


Exercises that enhance back hrrnia may also be used to prevent back injuries. While mechanical compression is still presumed to be of major importance, 2 — 4 leakage of nucleus pulposus NP from the disc core onto nervous tissue may also contribute to the experience of pain by causing a local inflammatory response and inducing both structural and functional changes in nerve roots. By using this site, you agree to the Terms nukeus Use and Privacy Policy.